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Table 2 Training-induced changes in the percentage of T-cell subsets among the different intervention groups in CMV seropositive participants

From: Six weeks of strength endurance training decreases circulating senescence-prone T-lymphocytes in cytomegalovirus seropositive but not seronegative older women

T-cell subsetIST (n = 21)SET (n = 16)CON (n = 20)Time effectaTime* group effectb
CD8+ T-cells
 CD8 + CD28 + CD57− (naive)
  CD8 − CD57+ (SPC)Baseline50.50 (27.75)60.75 (23.68)50.85 (31.53)0.3570.296
  6 weeks48.50 (33.70)*62.55 (26.47)52.25 (27.63)  
 CD8 + CD28− CD57− (memory)
  Baseline28.00 (22.55)33.10 (27.25)32.00 (23.17)0.0390.940
  6 weeks37.30 (25.70)30.45 (27.50)33.45 (23.75)  
 CD8 + CD57+ (SPC)
  Baseline5.60 (17.13)6.25 (11.55)7.45 (12.38)0.0120.161
  6 weeks6.70 (10.48)5.00 (6.50)**3.55 (15.63)  
 CD8 + CD28 − CD57+ (SPC)
  Baseline5.45 (16.50)6.15 (10.83)6.65 (11.73)0.0110.128
  6 weeks6.20 (10.03)4.65 (6.48)**3.30 (15.20)  
 CD8 + CD28 + CD57+ (SPC)
  Baseline0.25 (0.48)0.10 (0.38)0.20 (0.48)0.2490.673
  6 weeks0.20 (0.50)0.10 (0.43)0.15 (0.48)  
CD8− T-cells
  CD8 − CD28 + CD57− (naive)
  Baseline96.40 (5.35)96.55 (5.78)95.60 (5.45)0.7270.307
  6 weeks96.90 (5.35)97.20 (5.47)96.55 (7.17)  
 CD8 − CD28− CD57− (memory)
  Baseline1.80 (4.80)2.30 (4.50)2.75 (3.70)0.0910.701
  6 weeks2.10 (3.75)1.85 (4.33)2.55 (2.68)  
 CD8 − CD57+ (SPC)
  Baseline1.10 (2.60)0.75 (1.85)1.00 (2.63)0.0270.331
  6 weeks1.00 (1.80)0.40 (0.65)*0.80 (1.85)  
 CD8 − CD28 − CD57+ (SPC)
  Baseline1.00 (1.60)0.70 (1.68)0.90 (2.10)0.0340.337
  6 weeks0.80 (1.75)0.40 (0.48)*0.75 (1.55)  
 CD8 − CD28 + CD57+ (SPC)
  Baseline0.10 (0.40)0.10 (0.08)0.10 (0.35)0.1520.238
  6 weeks1.00 (0.15)0.05 (0.10)*0.10 (0.28)  
  1. Note: The values denote median (Interquartile range). CMV cytomegalovirus, SPC senescence-prone T-cells, IST intensive strength training, SET strength-endurance training, CON control. T-cell subsets were expressed as percentages within the CD3 + CD8+ or CD3 + CD8− T-cells. aResults of Wilcoxon signed-rank test for changes between baseline and 6 weeks for the entire CMV+ cohort; that is IST, SET and CON combined. bResults of Kruskal-Wallis test for changes between baseline and 6 weeks (a real numerical value was computed for each individual) among the 3 groups of training. Wilcoxon’s signed-rank test for within group differences: **p < 0.01 and *p < 0.05 significantly different from baseline within group