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Fig. 5 | Immunity & Ageing

Fig. 5

From: The presence of CLL-associated stereotypic B cell receptors in the normal BCR repertoire from healthy individuals increases with age

Fig. 5

Stereotypic BCR in the normal BCR repertoire of healthy aging individuals. a. Total frequency of stereotypic BCR in the normal BCR repertoire in naive mature B cells of healthy individuals. b-e. Frequency of stereotypic BCR assigned to CLL-associated stereotypic subsets in naive mature (b), non-switched (c), IgM-only (d), and CD27 + IgG+ switched (e) memory B cells. Statistical significance between different age groups was determined using the two-way ANOVA test (with Bonferroni multiple comparisons correction); *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001

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