Fig. 5From: The presence of CLL-associated stereotypic B cell receptors in the normal BCR repertoire from healthy individuals increases with ageStereotypic BCR in the normal BCR repertoire of healthy aging individuals. a. Total frequency of stereotypic BCR in the normal BCR repertoire in naive mature B cells of healthy individuals. b-e. Frequency of stereotypic BCR assigned to CLL-associated stereotypic subsets in naive mature (b), non-switched (c), IgM-only (d), and CD27 + IgG+ switched (e) memory B cells. Statistical significance between different age groups was determined using the two-way ANOVA test (with Bonferroni multiple comparisons correction); *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001Back to article page