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Fig. 6 | Immunity & Ageing

Fig. 6

From: Prime-pull vaccination with a plant-derived virus-like particle influenza vaccine elicits a broad immune response and protects aged mice from death and frailty after challenge

Fig. 6

Cytokine and chemokine levels in lung homogenates 3 days after challenge. Six weeks post-vaccination, female BALB/c mice (18–22 months) were challenged with A/California/07/2009 H1N1 and lungs were collected and homogenized 3 days post-infection to measure cytokines/chemokines by multiplex ELISA for the following cytokines: a IL-1α, IL-6, MCP-1, MIP-1α, RANTES and b IL-1β, IL-2, IL-3, IL-4, IL-5, IL-10, IL-12, IL-17, IFNγ, TNFα, GM-CSF. For statistical analysis, one-way ANOVA followed by Tukey’s multiple comparison test (**p < 0.01, * p < 0.05). Data represent 4–7 mice/group from one study. Error bars represent the standard error of the mean

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