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Table 2 HRs (95% CI) for all-cause, cardiovascular and cancer mortality stratified by baseline high-sensitivity C-reactive protein concentration quartiles

From: Associations of plasma high-sensitivity C-reactive protein concentrations with all-cause and cause-specific mortality among middle-aged and elderly individuals

HsCRP quartiles

All-cause mortality

Cardiovascular mortality

Cancer mortality

Model 1a

Model 2b

Model 1

Model 2

Model 1

Model 2

No. of participants

14,220

14,220

14,220

Person-years at risk

80,572

80,572

80,572

No. of events

1730

608

351

Q1

1.00 (reference)

1.00 (reference)

1.00 (reference)

1.00 (reference)

1.00 (reference)

1.00 (reference)

Q2

1.02 (0.88–1.17)

1.06 (0.92–1.22)

1.07 (0.84–1.36)

1.09 (0.82–1.33)

1.05 (0.76–1.44)

1.07 (0.78–1.48)

Q3

1.17 (1.02–1.35)*

1.18 (1.03–1.36)*

1.28 (1.01–1.62)*

1.26 (1.00–1.57)

1.23 (0.90–1.69)

1.23 (0.90–1.69)

Q4

1.59 (1.40–1.82)***

1.50 (1.31–1.72)***

1.62 (1.29–2.04)***

1.44 (1.13–1.82)**

1.71 (1.27–2.29)***

1.67 (1.23–2.26)**

P for trend

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

  1. aModel 1: adjusted for age and sex
  2. bModel 2: adjusted for age, sex, race, educational level, current smoking status, alcohol consumption, regular exercise, body mass index (BMI), household income, total cholesterol (TC) concentration, high density lipoprotein-cholesterol (HDL-C) concentration, hemoglobin A1c (HbA1c) at the endCES-D 8 score, hypertension, heart disease, stroke, diabetes, pulmonary disorder, psychiatric problems, and limitations in activities of daily living (ADLs)
  3. * P < 0.05; ** P < 0.01; *** P < 0.001