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Table 2 HRs (95% CI) for all-cause, cardiovascular and cancer mortality stratified by baseline high-sensitivity C-reactive protein concentration quartiles

From: Associations of plasma high-sensitivity C-reactive protein concentrations with all-cause and cause-specific mortality among middle-aged and elderly individuals

HsCRP quartiles All-cause mortality Cardiovascular mortality Cancer mortality
Model 1a Model 2b Model 1 Model 2 Model 1 Model 2
No. of participants 14,220 14,220 14,220
Person-years at risk 80,572 80,572 80,572
No. of events 1730 608 351
Q1 1.00 (reference) 1.00 (reference) 1.00 (reference) 1.00 (reference) 1.00 (reference) 1.00 (reference)
Q2 1.02 (0.88–1.17) 1.06 (0.92–1.22) 1.07 (0.84–1.36) 1.09 (0.82–1.33) 1.05 (0.76–1.44) 1.07 (0.78–1.48)
Q3 1.17 (1.02–1.35)* 1.18 (1.03–1.36)* 1.28 (1.01–1.62)* 1.26 (1.00–1.57) 1.23 (0.90–1.69) 1.23 (0.90–1.69)
Q4 1.59 (1.40–1.82)*** 1.50 (1.31–1.72)*** 1.62 (1.29–2.04)*** 1.44 (1.13–1.82)** 1.71 (1.27–2.29)*** 1.67 (1.23–2.26)**
P for trend < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001
  1. aModel 1: adjusted for age and sex
  2. bModel 2: adjusted for age, sex, race, educational level, current smoking status, alcohol consumption, regular exercise, body mass index (BMI), household income, total cholesterol (TC) concentration, high density lipoprotein-cholesterol (HDL-C) concentration, hemoglobin A1c (HbA1c) at the endCES-D 8 score, hypertension, heart disease, stroke, diabetes, pulmonary disorder, psychiatric problems, and limitations in activities of daily living (ADLs)
  3. * P < 0.05; ** P < 0.01; *** P < 0.001