Fig. 4From: Senescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotypeEffect of fenofibrate treatment in TNFα-induced senescent SF. 14-day senescent (SEN) and control (CT) SF were treated with fenofibrate (FB, 25 μM) for 72 h. Graphics show the changes in CDKN2A and SASP factors IL6, CXCL8, MMP3 and CCL2 mRNA expression in relation to untreated CT SF (n = 7) (*Wilcoxon test)Back to article page