Fig. 2

HRs for the combined associations of hs-CRP and CI with all-cause mortality according to sensitivity analysis (Panel a) and specified subgroups, stratified by age (< vs. ≥ 90 y; Panel b) and sex (Panel c). All models were adjusted for age (not in Panel b) and sex (not in Panel c), drinking, smoking, marital status, regular exercise, medication, BMI, central obesity, self-reported history of hypertension, diabetes mellitus, heart disease, stroke and cerebrovascular disease, respiratory disease and cancer. Group 1 (hs-CRP ≤ 3.0 mg/L and normal cognition), group 2 (hs-CRP > 3.0 mg/L and normal cognition), group 3 (hs-CRP ≤ 3.0 mg/L and CI), group 4 (hs-CRP > 3.0 mg/L and CI). Group symbols are as follows: ▲ group 2, ■ group 3, ● group 4), the estimated HRs for each group are compared with group 1 (HR = 1.0, not shown)