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Table 2 Immunological T cell parameters of renal allograft recipients prior to transplantation

From: A very low thymus function identifies patients with substantial increased risk for long-term mortality after kidney transplantation

 

Alive (n = 181)*

Deceased (n = 30)*

p-value

Total CD4 T cells

720 (418)**

404 (203)

0.001

Naive CD4 T cells

207 (233)

94 (78)

< 0.001

Naïve CD4 CD31pos T cells

119 (156)

59 (59)

< 0.001

Naive CD4 CD31neg T cells

66 (84)

35 (35)

< 0.001

Memory CD4 T cells

471 (273)

321 (205)

0.018

Central memory CD4 T cells

289 (223)

169 (147)

0.004

Effector memory CD4 T cells

155 (124)

117 (153)

0.4

Temra CD4 T cells

10 (17)

7 (11)

0.1

CD28null memory CD4 T cells

16 (53)

25 (69)

0.4

Total CD8 T cells

356 (231)

381 (565)

0.3

Naïve CD8 T cells

67 (91)

27 (35)

< 0.001

Naïve CD8 CD31pos T cells

64 (89)

26 (30)

< 0.001

Naive CD8 CD31neg T cells

2 (2)

1 (3)

0.6

Memory CD8 T cells

256 (208)

299 (571)

0.039

Central memory CD8 T cells

16 (21)

14 (15)

0.7

Effector memory CD8 T cells

109 (94)

125 (214)

0.2

Temra CD8

97 (153)

149 (340)

0.2

CD28null memory CD8 T cells

119 (172)

172 (399)

0.1

CD4/CD8 T cell ratio

2.0 (1.6)

1.2 (1.3)

0.008

CMV seropositive***

57.8%

66.7%

0.6

  1. *Recipients alive and deceased at time of follow-up, **cell numbers are expressed in cells/μL in medians with interquartile range between parenthesis, ***percentage of recipients with detectable serum anti-cytomegalovirus antibodies