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Table 4 Analysis of STING 293Q allele effects on certain aging-related diseases in obese subjects

From: First evidence for STING SNP R293Q being protective regarding obesity-associated cardiovascular disease in age-advanced subjects – a cohort study

Diseases (N: cases/controls)

P-value

OR (95%CI)

Aging-related diseases (683/231)*

0.014

0.651 (0.462–0.917)

CVD (127/231)

0.010

0.490 (0.285–0.841)

Chronic lung diseases (57/231)

0.062

0.492 (0.233–1.037)

Cancer (10/231)

0.529

0.601 (0.123–2.927)

DM-T2 (88/231)

0.375

0.776 (0.443–1.359)

Cognitive impairment (92/231)

0.554

0.835 (0.459–1.518)

  1. Analysis was done by logistic regression using SPSS Statistic software package (version 20.0 IBM, Munich, Germany) with STING R/R as reference and combined R/Q and Q/Q genotypes as predictor, and correction for age, sex and former smoking. * 17 samples were excluded from the analysis due to the incomplete disease record
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Immunity & Ageing

ISSN: 1742-4933

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