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Table 4 Analysis of STING 293Q allele effects on certain aging-related diseases in obese subjects

From: First evidence for STING SNP R293Q being protective regarding obesity-associated cardiovascular disease in age-advanced subjects – a cohort study

Diseases (N: cases/controls)P-valueOR (95%CI)
Aging-related diseases (683/231)*0.0140.651 (0.462–0.917)
CVD (127/231)0.0100.490 (0.285–0.841)
Chronic lung diseases (57/231)0.0620.492 (0.233–1.037)
Cancer (10/231)0.5290.601 (0.123–2.927)
DM-T2 (88/231)0.3750.776 (0.443–1.359)
Cognitive impairment (92/231)0.5540.835 (0.459–1.518)
  1. Analysis was done by logistic regression using SPSS Statistic software package (version 20.0 IBM, Munich, Germany) with STING R/R as reference and combined R/Q and Q/Q genotypes as predictor, and correction for age, sex and former smoking. * 17 samples were excluded from the analysis due to the incomplete disease record