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Table 6 Analysis of STING 293Q allele effects on certain aging-related diseases in obese subjects and current smokers

From: First evidence for STING SNP R293Q being protective regarding obesity-associated cardiovascular disease in age-advanced subjects – a cohort study

Diseases (N: cases/controls)P-valueOR (95%CI)
Aging-related diseases (885/346)< 0.0000.567 (0.426–0.754)
CVD (157/346)0.0020.467 (0.291–0.749)
Chronic lung diseases (83/346)0.0230.495 (0.270–0.907)
Cancer (15/346)0.3970.573 (0.158–2.081)
DM-T2 (117/346)0.0950.660 (0.405–1.075)
Cognitive impairment (119/346)0.2890.758 (0.454–1.265)
  1. Analysis was done by logistic regression using SPSS Statistic software package (version 20.0 IBM, Munich, Germany) with STING R/R as reference and combined R/Q and Q/Q genotypes as predictor and correction for age and sex