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Table 6 Analysis of STING 293Q allele effects on certain aging-related diseases in obese subjects and current smokers

From: First evidence for STING SNP R293Q being protective regarding obesity-associated cardiovascular disease in age-advanced subjects – a cohort study

Diseases (N: cases/controls)

P-value

OR (95%CI)

Aging-related diseases (885/346)

< 0.000

0.567 (0.426–0.754)

CVD (157/346)

0.002

0.467 (0.291–0.749)

Chronic lung diseases (83/346)

0.023

0.495 (0.270–0.907)

Cancer (15/346)

0.397

0.573 (0.158–2.081)

DM-T2 (117/346)

0.095

0.660 (0.405–1.075)

Cognitive impairment (119/346)

0.289

0.758 (0.454–1.265)

  1. Analysis was done by logistic regression using SPSS Statistic software package (version 20.0 IBM, Munich, Germany) with STING R/R as reference and combined R/Q and Q/Q genotypes as predictor and correction for age and sex
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Immunity & Ageing

ISSN: 1742-4933

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