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Fig. 3 | Immunity & Ageing

Fig. 3

From: Moderate- to high intensity aerobic and resistance exercise reduces peripheral blood regulatory cell populations in older adults with rheumatoid arthritis

Fig. 3

Changes in CD24hiCD38hi B cells (Bregs), IL-10 and MDSCs in peripheral blood in response to 20 weeks of exercise intervention in older adults with RA. a. Paired measurements of the CD24hiCD38hi B cell frequencies (related to the CD19+ gate) in blood pre and post 20 weeks of control (n = 20) or exercise (n = 22) intervention and b. IL-10 (pg/ml) in plasma, pre and post 20 weeks of control (n = 24) or exercise (n = 24) intervention. c. Paired measurements of the frequencies of CD33 + CD11b + MDSCs and d. MDSC subsets: CD14hi, CD14loCD15- and CD15+ in blood, pre and post 20 weeks of control (n = 24) or exercise (n = 24) intervention. P values were determined using Wilcoxon signed-rank test comparing data obtained at baseline (pre) and after 20 weeks (post). The Mann-Whitney U test was used for comparison between the two groups. *p ≤ 0.05 ** p ≤ 0.01 *** p ≤ 0.001 **** p ≤ 0.0001

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Immunity & Ageing

ISSN: 1742-4933

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