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Fig. 1 | Immunity & Ageing

Fig. 1

From: The impact of body mass index on adaptive immune cells in the human bone marrow

Fig. 1

Levels of cytokines and ROS in the BM are affected by BMI. The mean fluorescence intensity (MFI) of (a) IL-15 and (b) IL-6 measured using flow cytometry in persons with BMI < 25 and BMI > 30 is shown. Unpaired t test, *p < 0.05. Data are reported as mean ± SEM. Relationship between ROS levels (=DHE MFI) (c), frequency of IFNγ+CD8+ T cells (d), TNF+CD8+ T cells (e) in BMMCs and BMI. Correlation between IFNγ+CD4+ T cells (f) and TNF+CD4+ T cells (g) in PBMCs and BMI. Spearman coefficient (rs), sample number (N), and p-values are reported in each graph. Representative histograms showing the intensity of IL-15, IL-6 and DHE in donors with BMI < 25 (BMI = 23.2) and BMI > 30 (BMI = 34.6) are shown

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