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Table 2 Correlations between CD4+ T cell subsets, expression of PD-1 and IL-7Rα within CD4+ T cell subsets in the BM and BMI

From: The impact of body mass index on adaptive immune cells in the human bone marrow

 AllCMVCMV+
 rsp valuersp valuersp value
CD4+T cells (of CD3+)0.360.020.380.010.120.59
CCR7+CD45RA+(CD4+TN)0.450.0020.230.350.510.02
CCR7+CD45RA(CD4+TCM)0.340.03− 0.180.460.590.01
CCR7CD45RA(CD4+TEM)− 0.030.87− 0.150.53− 0.580.01
CCR7CD45RA+(CD4+TEMRA)0.340.050.430.040.410.05
CD4+CD28− 0.020.91− 0.160.50− 0.010.96
CD4+CD57+0.001.000.160.420.270.91
CD4+PD-1+−0.200.73− 0.410.04− 0.390.08
CD4+IL-7Rα+0.430.030.370.120.030.91
PD-1+CD4+TCM−0.360.02− 0.210.39− 0.220.34
PD-1+CD4+TEM−0.390.01−0.490.03−0.160.48
CD57+CD4+TEM−0.190.22−0.020.930.140.55
PD-1+CD4+TEMRA−0.330.10−0.190.440.010.97
CD57+CD4+TEMRA−0.030.85−0.010.980.190.39
  1. Spearman correlation coefficients (rs) and p values for CMV and CMV+ persons and for the whole cohort are shown. p < 0.05 was considered significant. For all subpopulations, NCMV = 20, NCMV+ = 19, Nall = 39. Detailed gating strategy used to define the populations are shown in Fig. 3
  2. Statistically significant values are shown in bold