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Table 3 Adjusted hazard ratios of time to treatment failure

From: Frontline treatments in extremely elderly patients with diffuse large B-cell lymphoma: a population-based study in Taiwan, 2010–2015

VariableAged between 60 and 79 yearsAged more than 80 years
HR(95%CI)p-valueHR(95%CI)p-value
Frontline treatment
 R-CHOP1 < 0.00011 < 0.0001
 R-CVP1.64(1.43–1.88) 1.52(1.22–1.91) 
 CHOP4.49(3.63–5.57) 3.58(2.21–5.81) 
 CVP6.70(5.08–8.82) 3.00(2.11–4.29) 
Gender
 male1 0.02711 0.4817
 female0.88(0.79–0.99) 0.93(0.75–1.14) 
Age1.01(1.00–1.02)0.13031.03(1.00–1.05)0.0915
Ann Arbor stage
 I1 < 0.00011 < 0.0001
 II1.40(1.14–1.72) 1.22(0.85–1.74) 
 III2.24(1.83–2.74) 1.57(1.12–2.20) 
 IV3.12(2.58–3.77) 2.24(1.62–3.09) 
Radiotherapy
 No1 0.67401 0.1561
 Yes1.03(0.90–1.19) 0.82(0.62–1.08) 
Carlson comorbidity index
 01 0.00081 0.7690
 11.07(0.93–1.23) 1.03(0.80–1.34) 
 2+1.27(1.12–1.45) 1.09(0.85–1.40) 
Practice setting
 medical center1 0.38681 0.5453
 others1.05(0.94–1.18) 0.94(0.76–1.16)