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Fig. 7 | Immunity & Ageing

Fig. 7

From: IL-15 deficiency alleviates steroid-induced osteonecrosis of the femoral head by impact osteoclasts via RANKL-RANK-OPG system

Fig. 7

IL-15 deficiency decreased the amount of CFU-GM/CFU-M and inhibited osteoclasts formation. The numbers of CFU-GM (a) and CFU-M (b) differentiated from bone marrow-derived cells were significantly decreased by IL-15 deficiency. c Osteoclast formation increased in the osteonecrosis group, and IL-15 deficiency significantly attenuated the osteoclasts maturation. The data were expressed as means ± SD (n = 6). **p < 0.01 versus the WT ON group

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