Severity p-value | Δa-da p-value | n | mean | median | SDb | IQRc | |
---|---|---|---|---|---|---|---|
Age | < 0.001(A) | ||||||
Mild | 160 | 58.96 | 61.00 | 17.08 | 49–70.5 | ||
Moderate | 246 | 64.08 | 66.00 | 16.05 | 54–77 | ||
Severe | 178 | 65.25 | 65.50 | 15.98 | 54–79 | ||
On admission | |||||||
IL6d (pg/mL) | < 0.001 | ||||||
Mild | 78 | 31.40 | 17.60 | 40.53 | 9–40.9 | ||
Moderate | 98 | 77.86 | 43.10 | 155.30 | 19.5–87.3 | ||
Severe | 78 | 241.16 | 87.45 | 597.92 | 30.4–239.7 | ||
CRPe (mg/L) | < 0.001 | ||||||
Mild | 132 | 66.21 | 44.45 | 67.83 | 17.45–85.2 | ||
Moderate | 231 | 108.82 | 93.00 | 83.25 | 43.8–147 | ||
Severe | 160 | 152.14 | 128.40 | 107.91 | 64.25–217.65 | ||
ferritin (ng/mL) | < 0.001 | ||||||
Mild | 80 | 711.39 | 491.45 | 881.96 | 201.65–874 | ||
Moderate | 133 | 1003.30 | 775.00 | 902.63 | 390–1479 | ||
Severe | 84 | 1653.65 | 1073.50 | 2404.04 | 713.5–1796.5 | ||
D-dimer (ng/mL) | < 0.001 | ||||||
Mild | 120 | 1083.58 | 522.00 | 3684.33 | 340.5–797 | ||
Moderate | 200 | 1442.13 | 594.00 | 3878.02 | 391.5–1025 | ||
Severe | 136 | 3243.72 | 960.50 | 13,804.06 | 468.5–1586 | ||
LDHf (U/L) | < 0.001 | ||||||
Mild | 124 | 252.55 | 244.50 | 75.01 | 200–292.5 | ||
Moderate | 208 | 314.61 | 292.50 | 123.08 | 240–372.5 | ||
Severe | 135 | 438.99 | 401.00 | 274.08 | 279–524 | ||
Leucocyte count (cells*103/μL) | < 0.001 | ||||||
Mild | 147 | 6.25 | 5.70 | 2.46 | 4.68–7.03 | ||
Moderate | 246 | 7.60 | 6.15 | 7.16 | 4.70–8.82 | ||
Severe | 177 | 8.65 | 7.89 | 4.73 | 5.50–10.3 | ||
Neutrophil count (cells*103/μL) | < 0.001 | ||||||
Mild | 147 | 4.33 | 3.89 | 2.22 | 3.00–5.17 | ||
Moderate | 246 | 5.39 | 4.32 | 3.74 | 3.20–7.00 | ||
Severe | 177 | 7.10 | 6.40 | 4.13 | 4.30–8.71 | ||
Lymphocyte count (cells*103/μL) | 0.048 | ||||||
Mild | 147 | 1.29 | 1.10 | 0.76 | 0.86–1.57 | ||
Moderate | 246 | 1.13 | 0.97 | 0.85 | 0.73–1.33 | ||
Severe | 177 | 1.10 | 0.90 | 1.47 | 0.59–1.24 | ||
Lymphocyte % | < 0.001 | ||||||
Mild | 147 | 22.04 | 19.70 | 11.14 | 14.7–28.7 | ||
Moderate | 246 | 18.55 | 17.10 | 10.99 | 9.8–24.5 | ||
Severe | 177 | 14.64 | 12.00 | 11.01 | 7.5–18.1 | ||
CD3 + CD4+ % | |||||||
Mild | 8 | 41.31 | 41.10 | 6.56 | 36–47.1 | ||
Moderate | 35 | 45.84 | 46.50 | 12.52 | 38.3–52.8 | ||
Severe | 12 | 41.04 | 41.90 | 11.25 | 34.3–50.4 | ||
CD3 + CD4+ count (cells*103/μL) | |||||||
Mild | 8 | 0.74 | 0.71 | 0.46 | 0.32.35–1.1 | ||
Moderate | 33 | 0.56 | 0.44 | 0.39 | 0.27–0.69 | ||
Severe | 13 | 0.36 | 0.32 | 0.20 | 0.27–0.46 | ||
CD3 + CD8+ % | |||||||
Mild | 8 | 26.23 | 27.00 | 4.26 | 22.7–28.9 | ||
Moderate | 35 | 21.74 | 20.30 | 10.66 | 12.09–30.5 | ||
Severe | 12 | 26.57 | 28.30 | 9.18 | 19.39–32.4 | ||
CD4 + CD8+ count (cells*103/μL) | 0.041(A) | ||||||
Mild | 8 | 0.45 | 0.41 | 0.28 | 0.20–0.70 | ||
Moderate | 33 | 0.25 | 0.18 | 0.20 | 0.13–0.35 | ||
Severe | 13 | 0.24 | 0.24 | 0.18 | 0.084–0.30 | ||
CD19+ % | |||||||
Mild | 8 | 11.50 | 10.90 | 3.36 | 8.95–13 | ||
Moderate | 35 | 12.47 | 10.60 | 6.99 | 7.3–16 | ||
Severe | 9 | 15.97 | 12.00 | 10.61 | 10.3–14.83 | ||
CD19+ count (cells*103/μL) | |||||||
Mild | 8 | 0.19 | 0.18 | 0.11 | 0.09–0.29 | ||
Moderate | 33 | 0.12 | 0.09 | 0.09 | 0.06–0.20 | ||
Severe | 10 | 0.16 | 0.10 | 0.08 | 0.06–0.12 | ||
Natural Killer % | |||||||
Mild | 8 | 15.59 | 13.80 | 8.96 | 8.55–23.55 | ||
Moderate | 35 | 16.06 | 15.50 | 8.36 | 11.8–20.7 | ||
Severe | 9 | 15.67 | 11.40 | 10.90 | 6.8–20.6 | ||
Natural Killer count (cells*103/μL) | |||||||
Mild | 8 | 0.23 | 0.16 | 0.15 | 0.12–0.37 | ||
Moderate | 33 | 0.17 | 0.16 | 0.12 | 0.08–0.21 | ||
Severe | 10 | 0.11 | 0.12 | 0.06 | 0.09–0.14 | ||
IgG (mg/dL) | 0.048 | ||||||
Mild | 1 | 1006.00 | 1006.00 | . | 1006–1006 | ||
Moderate | 13 | 998.31 | 934.00 | 133.23 | 915–1071 | ||
Severe | 5 | 857.20 | 862.00 | 76.43 | 788–885 | ||
IgA (mg/dL) | |||||||
Mild | 1 | 248.00 | 248.00 | . | 248–248 | ||
Moderate | 13 | 234.00 | 223.00 | 86.48 | 175–248 | ||
Severe | 5 | 219.40 | 218.00 | 28.98 | 213–230 | ||
IgM (mg/dL) | 0.009 | ||||||
Mild | 1 | 129.00 | 129.00 | . | 129–129 | ||
Moderate | 13 | 118.00 | 121.00 | 34.88 | 88–141 | ||
Severe | 5 | 59.20 | 58.00 | 13.83 | 50–72 | ||
At discharge | |||||||
IL6 (pg/mL) | 0.017 | ||||||
Mild | 55 | 21.17 | 11.60 | 28.51 | 4.77–23.2 | ||
Moderate | < 0.001 | 50 | 47.04 | 7.26 | 126.46 | 1.88–13.4 | |
Severe | 12 | 677.75 | 24.86 | 2204.56 | 9.1–59.63 | ||
CRP (mg/L) | < 0.001 | ||||||
Mild | 115 | 27.69 | 14.30 | 32.92 | 6.3–38.1 | ||
Moderate | 137 | 29.93 | 13.93 | 42.69 | 4–36 | ||
Severe | 45 | 35.86 | 8.00 | 71.26 | 4–25.2 | ||
ferritin (ng/mL) | < 0.001 | ||||||
Mild | 77 | 611.96 | 386.00 | 646.97 | 245–793 | ||
Moderate | 94 | 778.67 | 687.50 | 599.84 | 331–1178 | ||
Severe | 38 | 3783.41 | 1085.90 | 15,135.72 | 571–1776 | ||
D-dimer (ng/mL) | < 0.001 | ||||||
Mild | 94 | 705.22 | 463.50 | 937.24 | 326–751 | ||
Moderate | 130 | 5219.08 | 586.00 | 48,290.67 | 356–1040 | ||
Severe | < 0.001 | 47 | 2870.13 | 1415.00 | 4230.08 | 792–3912 | |
LDH (U/L) | < 0.001 | 0.004 | |||||
Mild | 102 | 238.22 | 218.00 | 78.79 | 192–261 | ||
Moderate | 124 | 247.19 | 235.50 | 83.32 | 192–271 | ||
Severe | 47 | 820.53 | 286.00 | 2722.15 | 242–400 | ||
Leucocyte count (cells*103/μL) | < 0.001 | 0.013 | |||||
Mild | 127 | 6.26 | 5.80 | 2.59 | 4.78–7.21 | ||
Moderate | 146 | 7.46 | 6.90 | 3.08 | 5.30–9.20 | ||
Severe | 53 | 10.10 | 8.31 | 6.41 | 5.79–12.33 | ||
Neutrophil count (cells*103/μL) | < 0.001 | ||||||
Mild | < 0.001 | 127 | 4.12 | 3.54 | 2.56 | 2.67–4.50 | |
Moderate | 146 | 5.07 | 4.40 | 2.99 | 3.09–6.20 | ||
Severe | 53 | 8.01 | 6.50 | 6.18 | 3.78–9.60 | ||
Lymphocyte count (cells*103/μL) | < 0.001 | ||||||
Mild | 127 | 1.50 | 1.45 | 0.62 | 1.06–1.89 | ||
Moderate | 146 | 1.54 | 1.40 | 0.87 | 0.97–1.87 | ||
Severe | 53 | 1.52 | 1.54 | 0.77 | 0.8–2.02 | ||
Lymphocyte % | 0.006 | 0.007 | |||||
Mild | 127 | 25.47 | 26.10 | 9.31 | 19.4–32.1 | ||
Moderate | 146 | 23.12 | 22.65 | 12.73 | 13.7–30.3 | ||
Severe | 53 | 19.41 | 18.40 | 13.34 | 8.6–26.6 | ||
CD3 + CD4+ % | |||||||
Mild | 3 | 49.33 | 54.00 | 13.61 | 34–60 | ||
Moderate | 11 | 47.66 | 53.00 | 16.84 | 49–58.24 | ||
Severe | 0 | ||||||
CD3 + CD8+ % | |||||||
Mild | 3 | 20.33 | 20.00 | 11.50 | 9–32 | ||
Moderate | 11 | 19.50 | 17.00 | 10.22 | 10–29.27 | ||
Severe | 0 | ||||||
CD19% | |||||||
Mild | 3 | 15.00 | 17.00 | 6.24 | 8–20 | ||
Moderate | 11 | 17.51 | 10.86 | 22.97 | 7–15 | ||
Severe | 0 | ||||||
Natural Killer % | |||||||
Mild | 3 | 13.67 | 15.00 | 4.16 | 9–17 | ||
Moderate | 11 | 12.85 | 11.00 | 8.38 | 7–17.3 | ||
Severe | 0 |