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Fig. 2 | Immunity & Ageing

Fig. 2

From: Alterations of monocyte NF-κB p65/RelA signaling in a cohort of older medical patients, age-matched controls, and healthy young adults

Fig. 2

Monocyte subsets and HLA-DR expression. a Representative dot plot for the gating strategy for the CD14 CD16 monocyte subsets. b CD14 CD16 monocyte subset distribution in the Patient Group at admission (n = 42) and 30-day follow-up (n = 50), and Older (n = 52) and Young (n = 59) Control groups. Paired t-test was used for comparison between Patient Group and Older Controls, unpaired t-test was used for comparison between Older and Young Controls. c Total CD14 CD16 monocyte and subsets HLA-DR expression levels for the Patient Group at admission (n = 48 for total monocyte and 42 for subsets) and at the 30-day follow-up (n = 52 for total monocyte and 50 for subsets), and Older (n = 52) and Young (n = 59) Controls. Wilcoxon signed-rank test was used for comparisons between Patient Group at admission and 30-day follow-up, and between Patient Group at 30-day follow-up and Older Controls, Wilcoxon rank-sum test was used for comparison between Older and Young Controls. Box plots depict median and IQR, error bars indicate 95% CI. * indicates a p-value < 0.05

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