Fig. 3

Basal and induced pNF-κB levels in monocytes. a Basal pNF-κB levels in monocytes from the Patient Group at admission (n = 46) and at follow-up (n = 52), Older Controls (n = 52) and Young Controls (n = 59). b Fold change in pNF-κB levels in monocytes from the Patient Group at admission (n = 36) and at follow-up (n = 50), Older Controls (n = 52) and Young Controls (n = 19) after stimulation with LPS for 15 min. c Fold change in pNF-κB levels in monocytes from the Patient Group at admission (n = 16) and at follow-up (n = 31), Older Controls (n = 52) and Young Controls (n = 19) after stimulation with TNF-α for 15 min. Wilcoxon signed-rank test was used for comparison between Patient Group at admission and 30-day follow-up and between Patient Group at 30-day follow-up and Older Controls, Wilcoxon rank-sum test was used for comparison between Older and Young Control groups. Box plots depict median and IQR, error bars indicate 95% CI. * indicates a p-value < 0.05