Table 3 Logistic regression for the probability of belonging to the Patient Group based on monocyte basal pNF-κB levels
OR Estimate | 95% CI | P-value | |
|---|---|---|---|
Unadjusted logistic regression | 1.80 | (1.3–2.4) | < 0.0001 |
Adjusted for | |||
Plasma biomarkers | |||
suPAR (ng/mL) | 1.78 | (1.3–2.5) | 0.0004 |
CRP (mg/L) | 1.75 | (1.3–2.4) | 0.0003 |
IL-6 (pg/mL) | 1.77 | (1.3–2.4) | 0.0001 |
IL-18 (pg/mL) | 1.86 | (1.4–2.5) | 0.0001 |
TNF-α (pg/mL) | 1.82 | (1.3–2.5) | 0.0002 |
GDF15 (pg/mL) | 1.69 | (1.2–2.3) | 0.0009 |
Frailty | |||
FI-OutRef | 1.79 | (1.2–2.6) | 0.003 |
Physical function | |||
4-m gait speed (m/s) | 1.81 | (1.3–2.5) | 0.0001 |
Hand grip strength (kg) | 1.77 | (1.3–2.4) | 0.0002 |
Chair stand test (repetitions) | 1.74 | (1.3–2.4) | 0.0005 |
Cognitive function | |||
MMSE (points) | 1.76 | (1.3–2.4) | 0.0002 |
Trail making test A (seconds) | 1.77 | (1.3–2.4) | 0.0004 |
Trail making test B (seconds) | 1.99 | (1.1–3.6) | 0.02 |
CMV IgG seropositivity | 1.82 | (1.3–2.5) | < 0.0001 |