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Table 1 Modulation of ARID3a in HSCs alters Myeloid/Lymphoid ratios

From: ARID3a expression in human hematopoietic stem cells is associated with distinct gene patterns in aged individuals

 

CD33+

CD19+

Myeloid/Lymphoida

Aged - media

196 ± 16

108 ± 15

1.81

  - control

262 ± 29

95 ± 26

2.76

  - ARID3a

270 ± 39

738 ± 89

0.36

Young - media

216 ± 30

156 ± 19

1.38

  - shCon

227 ± 30

228 ± 38

1.00

  - shA3a

212 ± 26

52 ± 10

4.08

  1. Average cell numbers ± SD for CD33 and CD19 expressing cells generated in mixed lineage differentiation cultures
  2. aMyeloid/lymphoid ratio of CD33+ and CD19+ cells
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Immunity & Ageing

ISSN: 1742-4933

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