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Table 1 Demographic and clinical characteristics of nAMD patients and controls

From: Plasma level of lipocalin 2 is increased in neovascular age-related macular degeneration patients, particularly those with macular fibrosis

 

All (N = 217)

Control (N = 43)

nAMD (N = 174)

P value

Age, mean (range)

77.3 (53–93)

73.4 (58–92)

78.3 (53–93)

0.001a

Female, number (%)

110 (51)

19 (44)

91 (52)

0.341b

Family history of AMD, number (%)

46 (21)

6 (14)

40 (23)

0.210b

History of hypertension, number (%)

133 (62)

23 (53)

110 (63)

0.312b

History of diabetes, number (%)

28 (13)

2 (5)

26 (15)

0.078b

History of cardiovascular disease, number (%)

57 (26)

9 (21)

48 (28)

0.416b

Smoking status

   

0.558b

 Non-smoker, number (%)

90 (42)

20 (47)

70 (40)

 

 Former smoker, number (%)

109 (51)

20 (47)

89 (51)

 

 Current smoker, number (%)

17 (8)

2 (5)

15 (9)

 

Body Mass Index (Mean ± SD)

26.0 ± 4.4

26.1 ± 5.1

26.0 ± 4.2

0.967c

Taking Cardiovascular Drugs, number (%)

156 (72)

28 (65)

128 (74)

0.370b

Taking Vitamins, number (%)

49 (23)

3 (7)

46 (26)

0.007b

Takin low-dose aspirin, number (%)

73 (34)

5 (12)

68 (39)

0.001b

  1. aMann Whitney U test
  2. bPearson’s chi-square test
  3. cIndependent sample t-test