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Table 1 Demographic and clinical characteristics of nAMD patients and controls

From: Plasma level of lipocalin 2 is increased in neovascular age-related macular degeneration patients, particularly those with macular fibrosis

  All (N = 217) Control (N = 43) nAMD (N = 174) P value
Age, mean (range) 77.3 (53–93) 73.4 (58–92) 78.3 (53–93) 0.001a
Female, number (%) 110 (51) 19 (44) 91 (52) 0.341b
Family history of AMD, number (%) 46 (21) 6 (14) 40 (23) 0.210b
History of hypertension, number (%) 133 (62) 23 (53) 110 (63) 0.312b
History of diabetes, number (%) 28 (13) 2 (5) 26 (15) 0.078b
History of cardiovascular disease, number (%) 57 (26) 9 (21) 48 (28) 0.416b
Smoking status     0.558b
 Non-smoker, number (%) 90 (42) 20 (47) 70 (40)  
 Former smoker, number (%) 109 (51) 20 (47) 89 (51)  
 Current smoker, number (%) 17 (8) 2 (5) 15 (9)  
Body Mass Index (Mean ± SD) 26.0 ± 4.4 26.1 ± 5.1 26.0 ± 4.2 0.967c
Taking Cardiovascular Drugs, number (%) 156 (72) 28 (65) 128 (74) 0.370b
Taking Vitamins, number (%) 49 (23) 3 (7) 46 (26) 0.007b
Takin low-dose aspirin, number (%) 73 (34) 5 (12) 68 (39) 0.001b
  1. aMann Whitney U test
  2. bPearson’s chi-square test
  3. cIndependent sample t-test