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Fig. 2 | Immunity & Ageing

Fig. 2

From: T cell phenotypes associated with insulin resistance: results from the Berlin Aging Study II

Fig. 2

Comparison of the distributions of metabolic parameters, immune cell subpopulation proportions, and cytokine levels in obese and non-obese insulin resistant (IR) and insulin sensitive (IS) participants. a-p Mann-Whitney U test was conducted to estimate differences between obese (BMI > 30 kg/m2) IS and IR, and non-obese (BMI < 30 kg/m2) IS and IR participants. a-h BMI (a), ISIOGTT (b), HOMA-IR (c), CRP levels (d), HbA1c (e), LDL cholesterol (f), triglycerides (g), and age (h) were compared between groups. i-p (i) Naïve CD8+ (TNAIVE, CD45RA+CCR7+ CD27+CD28+), (j) effector memory CD8+ T cells (TEM, CD45RA CD27CD28), (k) CD57+ CD8+ T cells, (l) IL-6 levels, (m) naïve CD4+ T cells (TNAIVE, CD45RA+CCR7+ CD27+CD28+), (n) effector memory CD4+ T cells (TEM, CD45RA CD27CD28), (o) central memory CD4+ T cells (TCM, CD45RA CD27+CD28+), (p) and IL-10 levels were compared between groups. Data are shown as mean ± SEM. * p < 0.05. **** p < 0.0001

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