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Fig. 2 | Immunity & Ageing

Fig. 2

From: Macrophage function in the elderly and impact on injury repair and cancer

Fig. 2

Strategies to target macrophages during age-related diseases. Potential strategies to target macrophages during ageing could include inhibiting recruitment via CSF-1R blockade (1), restoring metabolic function via inhibition of CD38 (2), targeting inflammageing via rapamycin/senolytics (3), anti-TNF (4), transfer of young serum/plasma/blood products (5), or reducing intracellular MAPK signalling leading to increased efferocytosis (6). Age-associated changes are shown as increased (↑); decrease (↓); unknown (?). This Figure was created with BioRender.com

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