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Table 2 Cell Frequencies Significantly Correlated Between Younger and/or Middle-aged Twins

From: Aging and CMV discordance are associated with increased immune diversity between monozygotic twins

Cell type Young twins Spearman’s rank correlation* Middle-aged twins Spearman’s rank correlation Young twins FDR-adjusted P Middle-aged twins FDR-adjusted P Older twins Spearman’s rank correlation from Brodin et al. [12]
IgD+ CD27- B cells 0.65 0.88 0.039 0.020 0.68
IgD- CD27+ B cells 0.70 0.86 0.020 0.020 0.6
IgD- CD27- B cells 0.72 0.87 0.020 0.020 0.56
CD16+ Monocytes 0.56 0.88 0.082 0.020 NA
CD4+ T cells 0.62 0.80 0.046 0.039 0.76
CD28+ CD4+ T cells 0.75 0.93 0.020 0.012 NA
CD8+ T cells 0.65 0.87 0.039 0.020 0.68
Effector Memory CD8+ T cells 0.61 0.73 0.053 0.071 0.9
CD94+ NK cells 0.55 0.78 0.083 0.039 NA
CD161+ CD45RA- Tregs 1.00 0.85 < 0.001 0.028 0.97
Tregs 0.80 0.67 0.015 0.095 0.24
B cells 0.67 0.43 0.038 0.34 0.25
IgD+ CD27+ B cells 0.53 0.47 0.095 0.27 0.51
Naïve B cells 0.67 0.28 0.039 0.52 0.85
Transitional B cells 0.73 0.55 0.020 0.19 0.28
Central Memory CD4+ T cells 0.64 0.38 0.041 0.40 0.55
CD94+ CD4+ T cells 0.73 0.25 0.020 0.56 NA
CD27+ CD4+ T cells 0.71 0.64 0.020 0.12 NA
CD161+ CD4+ T cells 0.72 0.52 0.020 0.23 NA
CD161- CD8+ T cells 0.64 0.32 0.040 0.47 NA
CD27- CD8+ T cells 0.58 0.32 0.071 0.47 NA
CD28- CD8+ T cells 0.63 0.28 0.045 0.52 NA
CD94+ CD8+ T cells 0.72 0.22 0.020 0.63 NA
CD85j + CD8+ T cells 0.54 0.35 0.095 0.45 NA
Effector CD8+ T cells 0.72 0.15 0.020 0.74 0.28
CD161- CD45RA+ Tregs 0.72 −0.06 0.020 0.15 0.66
CD161+ NK cells 0.71 0.58 0.020 0.17 NA
NKT cells 0.75 0.35 0.020 0.45 0.7
Lymphocytes 0.49 0.78 0.14 0.044 0.8
CD85j- CD4+ T cells 0.40 0.88 0.23 0.020 NA
Effector CD4+ T cells 0.46 0.78 0.19 0.039 0.7
  1. * Medians of the repeated calculations of Spearman’s rank correlation coefficients are reported (see methods)
  2. Statistically significant results (FDR-adjusted P < 0.1) are bolded