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Table 3 Cell Frequencies Significantly Correlated Between CMV−/− (n = 8 pairs) and/or CMV−/+ (n = 5 pairs) Twins

From: Aging and CMV discordance are associated with increased immune diversity between monozygotic twins

Cell type CMV −/− twins Spearman’s rank correlation* CMV −/+ twins Spearman’s rank correlation CMV −/− twins FDR-adjusted P CMV −/+ twins FDR-adjusted P
IgD- CD27- B cells 0.88 1.00 0.077 0.091
CD28+ CD4+ T cells 0.93 1.00 0.061 0.091
IgD+ CD27- B cells 0.95 0.10 0.047 0.95
IgD- CD27+ B cells 0.83 0.30 0.085 0.81
Transitional B cells 0.85 0.60 0.077 0.56
CD4+ T cells 0.83 0.50 0.091 0.66
CD85j- CD4+ T cells 0.93 0.10 0.047 0.95
CD8+ T cells 0.86 0.50 0.085 0.66
Effector memory CD8+ T cells 0.89 0.40 0.069 0.69
CD161+ CD45RA- Tregs 0.84 0.92 0.078 0.12
NKT cells 0.86 0.15 0.077 0.92
CD94+ NK cells 0.41 0.97 0.55 0.077
Tregs 0.78 1.00 0.12 0.091
  1. * For the CMV concordant negative twins, medians of the repeated calclations of Spearman’s rank correlations are reported (see methods)
  2. Statistically significant results (FDR-adjusted P < 0.1) are bolded