TY - JOUR AU - Frasca, Daniela AU - Romero, Maria AU - Garcia, Denisse AU - Diaz, Alain AU - Blomberg, Bonnie B. PY - 2021 DA - 2021/02/27 TI - Hyper‐metabolic B cells in the spleens of old mice make antibodies with autoimmune specificities JO - Immunity & Ageing SP - 9 VL - 18 IS - 1 AB - Aging is associated with increased intrinsic B cell inflammation, decreased protective antibody responses and increased autoimmune antibody responses. The effects of aging on the metabolic phenotype of B cells and on the metabolic programs that lead to the secretion of protective versus autoimmune antibodies are not known. SN - 1742-4933 UR - https://doi.org/10.1186/s12979-021-00222-3 DO - 10.1186/s12979-021-00222-3 ID - Frasca2021 ER -