Fig. 7
S. Typhi-specific responses of TI LPMC CD69+ CD103+ CD4+ TRM and CD69+ CD103- CD4+ TRM subsets in healthy adults and elderly volunteers following oral Ty21a-immunization. The net percentages of S. Typhi-specific responses (IFNγ+, IL-17A+, IL-2+, and TNFα+) in (a) CD69+ CD103+ CD4+ TRM and (b) CD69+ CD103- CD4+ TRM subsets were compared between adults (A- < 60 yrs.) and elderly (E- ≥ 60 yrs.) volunteers who were either Ty21a-vaccinated (red symbols) or unvaccinated (black symbols) with significant differences (*P < 0.05) indicated. Trends to exhibit significance are indicated by their p-values. Horizontal bars (black) represent median values