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Fig. 8 | Immunity & Ageing

Fig. 8

From: Age-dependency of terminal ileum tissue resident memory T cell responsiveness profiles to S. Typhi following oral Ty21a immunization in humans

Fig. 8

S. Typhi-specific responses of terminal ileum LPMC CD8+ TRM and CD8+ CD69+ CD103- T cell subsets in healthy adults and elderly volunteers following oral Ty21a immunization. The net percentages of S. Typhi-specific responses (IFNγ+, IL-17A+, IL-2+, and TNFα+) in (a) CD8+ TRM and (b) CD8+ CD69+ CD103- T cell subsets were compared between adults (A- < 60 yrs) and elderly (E- ≥ 60 yrs.) volunteers who were either Ty21a-vaccinated (red symbols) or unvaccinated (black symbols). Significant differences (*P < 0.05; **P < 0.005; ***P < 0.0005) are indicated. Trends to exhibit significance are indicated by their p-values. Horizontal bars (black) represent median values

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