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Fig. 2 | Immunity & Ageing

Fig. 2

From: High-dimensional single cell mass cytometry analysis of the murine hematopoietic system reveals signatures induced by ageing and physiological pathogen challenges

Fig. 2

Age related changes in the innate cell composition in spleen and bone marrow of SPF mice. a and d Identification of differentially distributed cellular phenotypes by t-SNE in concatenated spleen and bone marrow samples respectively (Young n = 6 and old n = 13). b and e The heatmaps show median marker intensities within each population in spleen and bone marrow respectively. c and f Selected innate populations were gated according to established lineage markers (Supplemental Fig. 1 for gating strategy). Line indicates mean, ± SD, *P < 0.05, **P < 0.01 ***P < 0.001 Mann-Whitney test. NS indicates non-significant changes

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Immunity & Ageing

ISSN: 1742-4933

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