Skip to main content
Fig. 3 | Immunity & Ageing

Fig. 3

From: High-dimensional single cell mass cytometry analysis of the murine hematopoietic system reveals signatures induced by ageing and physiological pathogen challenges

Fig. 3

Age related changes in the development of B cells in spleen and bone marrow of SPF mice. a and d Identification of differentially distributed cellular phenotypes by t-SNE in concatenated spleen and bone marrow samples respectively (Young n = 6 and old n = 13). b and e The heatmaps show median marker intensities within each population in spleen and bone marrow respectively. c and f Selected populations of B cells were gated according to established lineage markers (Supplemental Fig. 1 and 3B for gating strategy). Line indicates mean, ± SD, *P < 0.05, **P < 0.01 ***P < 0.001 Mann-Whitney test. NS indicates non-significant changes

Back to article page

Immunity & Ageing

ISSN: 1742-4933

Contact us