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Fig. 5 | Immunity & Ageing

Fig. 5

From: Analysis of the heterogeneity of the BCR H-CDR3 repertoire in the bone marrow and spleen of 3-, 12-, and 20-month old mice

Fig. 5

Insertion and deletion of nucleotides in the total sequences from mice of different ages. a Productive sequences. b Pseudogene sequences. c Out-of-frame sequences. The number of N1, N2, P3’V, P5’D and P5’J nucleotides added at the V-D-J junctions and the nucleotides deleted at 3’V, 5’D and 5’J by exonuclease trimming are shown (mean ± SD; error bars represent SD). The p values were determined using one-way ANOVA with a Bonferroni correction. All the statistically significant differences are indicated. * = p < 0.05, ** = p < 0.01, *** = p < 0.001

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