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Table 1 The BCR H-CDR3 repertoire of productive, pseudogene, and out-of-frame sequences in mice of different ages

From: Analysis of the heterogeneity of the BCR H-CDR3 repertoire in the bone marrow and spleen of 3-, 12-, and 20-month old mice

Sample

Productive

Total (unique)

Pseudogene

Total (unique)

Out of frame

Total (unique)

M3BM1

3,662,734 (474483)

107,165 (20484)

350,156 (89830)

M3BM2

4,201,156 (522977)

128,828 (21769)

331,242 (87427)

M3BM3

772,633 (386000)

16,473 (16473)

137,409 (75974)

M3BM4

1,357,086 (177848)

50,529 (8549)

305,304 (54945)

M3BM5

1,296,498 (178251)

42,892 (8104)

348,632 (61586)

M12BM1

1,438,032 (197994)

35,419 (6960)

97,826 (30317)

M12BM2

1,477,622 (156699)

58,100 (8877)

231,830 (45326)

M12BM3

502,958 (64768)

16,480 (2915)

98,908 (20059)

M12BM4

1,108,553 (184165)

34,074 (7926)

207,506 (51285)

M12BM5

1,669,642 (170188)

66,465 (8764)

324,449 (50027)

M20BM1

1,494,519 (242290)

39,108 (9174)

400,643 (87675)

M20BM2

1,316,534 (199635)

45,487 (9149)

277,021 (58823)

M20BM3

561,490 (120788)

19,500 (5264)

120,708 (31740)

M20BM4

429,629 (76188)

11,326 (2883)

78,493 (17853)

M20BM5

313,694 (67759)

8452 (2542)

48,381 (13366)

M3S1

4,523,881 (786508)

149,238 (33361)

865,160 (208318)

M3S2

4,017,413 (682554)

108,054 (25438)

663,139 (213543)

M3S3

4,417,442 (637351)

137,097 (28256)

784,674 (160134)

M3S4

3,942,536 (606347)

97,789 (22957)

808,071 (164970)

M3S5

2,696,776 (571503)

63,029 (18062)

446,298 (122955)

M3S7

1,091,791 (91001)

44,851 (4866)

226,582 (27110)

M3S8

46,895 (12469)

1165 (446)

6682 (2261)

M3S9

183,534 (27923)

5709 (1241)

34,871 (6784)

M12S1

1,044,884 (101677)

15,109 (3242)

266,668 (20675)

M12S2

1,365,544 (280774)

42,482 (11209)

212,575 (60657)

M12S3

1,382,706 (226375)

28,890 (7327)

217,936 (51437)

M12S4

1,555,800 (265748)

23,832 (7127)

329,043 (70801)

M12S5

1,441,200 (201908)

24,061 (5619)

267,609 (51811)

M12S7

737,198 (137061)

44,046 (7571)

57,282 (21271)

M12S8

880,181 (169410)

14,891 (4214)

65,870 (23320)

M12S9

77,364 (11970)

1056 (330)

4592 (1626)

M20S1

1,296,983 (134233)

24,433 (4355)

564,603 (37880)

M20S2

1,646,868 (205593)

43,362 (8512)

235,117 (46844)

M20S3

535,873 (125903)

10,757 (3624)

100,049 (29217)

M20S4

1,000,811 (172421)

22,525 (5906)

246,581 (49540)

M20S5

579,776 (156417)

16,389 (5813)

116,676 (36376)

M20S7

197,807 (22819)

5327 (923)

114,176 (6685)

M20S8

717,148 (68896)

18,116 (2575)

634,418 (24260)

M20S9

55,512 (6239)

2232 (327)

11,120 (1928)