Fig. 3From: miR-181a-regulated pathways in T-cell differentiation and agingMechanisms of reduced miR-181a levels in aged T cells. TCF1 and YY1 are the major transcription factors for transcription of pri-miR-181ab1. Age-related reduction of TCF1 and YY1 expression results in a loss of miR-181a expression in old naïve CD4 T cellsBack to article page