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Fig. 4 | Immunity & Ageing

Fig. 4

From: Metabolic phenotype of B cells from young and elderly HIV individuals

Fig. 4

B cells from young and elderly HIV individuals, as compared to those from healthy controls, are hyper-metabolic as evaluated by higher OCR and ECAR. B cells, isolated as described in Fig. 2, were left unstimulated. B cells were seeded into the wells of an extracellular flux analyzer at the concentration of 2 × 105/well in triplicate and run in a mitostress test. OCR results (a) and ECAR (b) results are shown. Open circles, young healthy donors; filled circles, elderly healthy donors; open squares, young HIV + individuals; filled circles, elderly HIV + individuals

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