Association of immunity markers with the risk of incident frailty: the Rugao longitudinal aging study

Immunity & Ageing

Table 3 Association of immunity markers with risk of incident frailty in all individuals

Immunity markers	Event/N (%)	Model 1		Model 2
		OR (95% CI)	P-value	OR (95% CI)	P-value
NLR	180/1149 (15.67%)
Q1 (≤ 1.26)	41/292 (14.04%)	Ref	Ref	Ref	Ref
Q2 (> 1.26, ≤1.71)	44/312 (14.10%)	1.00 (0.63, 1.59)	0.995	1.16 (0.67, 2.03)	0.590
Q3 (> 1.71, ≤2.35)	43/279 (15.41%)	1.12 (0.70, 1.78)	0.644	1.33 (0.77, 2.33)	0.309
Q4 (> 2.35)	52/266 (19.55%)	1.49 (0.95, 2.34)	0.082	2.39 (1.39, 4.21)	0.002
PLR	180/1149 (15.67%)
Q1 (≤ 71.07)	39/287 (13.59%)	Ref	Ref	Ref	Ref
Q2 (> 71.07, ≤93.79)	46/317 (14.51%)	1.08 (0.68, 1.72)	0.745	0.98 (0.57, 1.71)	0.954
Q3 (> 93.79, ≤126.81)	45/285 (15.79%)	1.19 (0.75, 1.89)	0.468	1.08 (0.63, 1.84)	0.787
Q4 (> 126.81)	50/260 (19.23%)	1.51 (0.96, 2.40)	0.075	1.35 (0.79, 2.32)	0.273
SII	180/1149 (15.67%)
Q1 (≤ 213.61)	38/295 (12.88%)	Ref	Ref	Ref	Ref
Q2 (> 213.61, ≤309.45)	45/307 (14.66%)	1.16 (0.73, 1.85)	0.538	1.37 (0.78, 2.44)	0.276
Q3 (> 309.45, ≤445.76)	46/293 (15.70%)	1.23 (0.77, 1.97)	0.380	1.55 (0.89, 2.73)	0.126
Q4 (> 445.76)	51/254 (20.08%)	1.70 (1.08, 2.70)	0.024	2.30 (1.32, 4.08)	0.004

NLR: neutrophil-lymphocytes ratio, PLR: platelet-to-lymphocyte ratio, SII: systemic immune-inflammation index, OR: odds ratio, CI: confidence interval, Model 1: unadjusted, Model 2: adjusted for age, gender, BMI, smoking, alcohol assumption, educational status, marital status, regular exercise, self-report hypertension, triglyceride, high-density lipoprotein, low-density lipoprotein, fasting blood glucose and comorbidity

ISSN: 1742-4933