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Fig. 1 | Immunity & Ageing

Fig. 1

From: Knockdown of lncRNA BDNF-AS inhibited the progression of multiple myeloma by targeting the miR-125a/b-5p-BCL2 axis

Fig. 1

BDNF-AS was upregulated, and miR-125a/b-5p were downregulated in MM serum and cell lines. a-c The expression of BDNF-AS (a), miR-125a-5p (b) and miR-125b-5p (c) in MM serum and healthy controls were detected by qRT-PCR (n = 30). (d) The overall survival of MM patients was evaluated by Kaplan-Meier curve based on the expression of BDNF-AS. (e and f) The correlations between the expression of BDNF-AS and miR-125a-5p (e) as well as BDNF-AS and miR-125b-5p (F) in MM serum was determined by Spearman’s correlation analysis (n = 30). (g-i) The expression of BDNF-AS (g), miR-125a-5p (h) and miR-125b-5p (I) in MM cell lines and normal plasma cells (nPC) was detected by qRT-PCR. *p < 0.05, **p < 0.01, ***p < 0.001

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