Fig. 4

Post Hoc Analysis of CD4+ T-Cell Dynamic Parameters. σ: production rate of naïve T-cells, α: activation rate constant of naïve T-cells that acquire a memory phenotype, dN: naïve T-cell death rate constant, dM: memory T-cell death rate constant. %CD31 on naïve CD4+ T-cells defines thymus output of naïve CD4+ T-cells, %PD-1/TIM-3 coexpression defines immune exhaustion. P values from the linear regression for each relation are indicated