Fig. 2
From: Impaired JAK-STAT pathway signaling in leukocytes of the frail elderly
Levels of phosphorylated STAT proteins (pSTAT1, pSTAT3, and pSTAT5), measured in CD4+ T cells, CD8+ T cells, B cells, and monocytes. Grey surface area with dashed outline shows baseline (unstimulated) pSTAT levels. Dark grey and orange surface areas with solid outline show pSTAT immune cell responses to stimulation in men and women, respectively. Shown are 20 out of 60 experimental stimuli conditions that induced a robust change (fold change > 2) compared to the baseline condition in CD4+, CD8+, B cells and monocytes