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Fig. 1 | Immunity & Ageing

Fig. 1

From: What’s happening where when SARS-CoV-2 infects: are TLR7 and MAFB sufficient to explain patient vulnerability?

Fig. 1

Shaath et al. (2020) have reported canonical pathways and upstream regulator networks associated with either mild or severe cases of SARS-CoV-2 (SC2). Bronchoalveolar samples from patients enabled a comparative transcriptomic analysis which tied an enhanced TLR7-expression to patients suffering from severe infection with SARS-CoV-2, whereas expression of the canonical miR146 was repressed in such patients compared to a mild severity of COVID-19 disease. For more genes differentially expressed refer to Shaath et al. (2020) [20]

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Immunity & Ageing

ISSN: 1742-4933

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