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Table 2 Demographic and clinical characteristics of SSc patients

From: Evidence of telomere attrition and a potential role for DNA damage in systemic sclerosis

Variables

SSc population (n = 174)

Age (median, IQR)

54 (21)

Gender, female, n (%)

151 (86.8)

Race, Caucasian, n (%)

169 (97.1)

Smoking history, n (%)

74 (42.5)

Comorbidities, n (%)

 Diabetes mellitus

15 (8.6)

 Hypertension

42 (24.1)

 Dyslipidemia

40 (23.0)

 MACE

11 (6.3)

 Cancer

14 (8.1)

Disease duration1 median (IQR), years

7 (10)

Disease subtype, n (%)

 lcSSc

105 (60.3)

 dcSSc

69 (39.6)

Autoantibodies, n (%)

 ATA

54 (31.0)

 ACA

62 (35.6)

Clinical involvement of SSc, n (%)

 Pulmonary hypertension

17 (9.8)

 Pulmonary (ILD)

57 (32.7)

 Cardiac

29 (16.7)

 Gastrointestinal

137 (78.7)

 Renal

7 (4.0)

Previous Therapy, n (%)

 Glucocorticoids

98 (56.3)

 Immunosuppressive drugs2

80 (46.0)

 Maximal mRSS ever, median (IQR), range 0–51

10 (19)

 Death by any cause, n (%)

34 (19.5)

  1. 1From first non-Raynaud disease manifestation. 2Azathioprine, Methotrexate, Cyclophosphamide, Mycophenolate mofetil, Rituximab or Leflunomide. (ILD) Interstitial lung disease. lcSSc limited cutaneous SSc, dcSSc diffuse cutaneous SSc, ATA anti-topoisomerase I antibodies, ACA anticentromere antibodies, n number, mRSS modified Rodnan skin score. Clinical definitions are described in Additional file 1 and according to reference [25]