Salutary effects of moderate but not high intensity aerobic exercise training on the frequency of peripheral T-cells associated with immunosenescence in older women at high risk of breast cancer: a randomized controlled trial

Table 3 The numbers of CD4+ and CD8+ T-cell subsets in peripheral blood before and after the 12-week intervention. N=naïve, CM=central memory, EM=effector memory, EMRA= CD45RA⁺ Effector Memory, RTE=recent thymic emigrants. Data are mean (SD) with bolded p-values indicating p<0.05

T-cell Subset			Pre (cells/µl WB)	Post (cells/µl WB)	p	\|Hedge’s g\|
CD4+	Naïve	HIIT*	264.03 (133.13)	163.46 (79.56)	0.02	0.87
		MICT	148.70 (94.68)	178.94 (109.27)	0.17	0.28
		UC	190.23 (97.01)	177.37 (131.75)	0.6	0.1
	CD4 Naïve CD31+ (RTE)	HIIT*	227.36 (105.46)	142.48 (62.28)	0.01	0.93
		MICT	134.54 (86.43)	154.74 (95.08)	0.3	0.21
		UC	172.14 (90.48)	158.42 (123.98)	0.55	0.12
	CM	HIIT	225.62 (76.13)	173.93 (59.4)	0.07	0.72
		MICT	223.88 (107.66)	287.67 (134.81)	0.01	0.49
		UC	270.94 (176.45)	224.46 (178.24)	0.3	0.25
	EM	HIIT	191.09 (68.62)	132.26 (77.17)	0.05	0.76
		MICT	189.59 (90.57)	194.86 (90.08)	0.82	0.06
		UC	240.05 (161.12)	171.61 (119.61)	0.22	0.45
	EMRA	HIIT	39.71 (39.04)	22.26 (16.32)	0.28	0.55
		MICT	20.65 (12.36)	19.35 (10.55)	0.73	0.11
		UC	27.82 (20.55)	26.56 (21.02)	0.66	0.06
CD8+	Naïve	HIIT	98.83 (68.05)	95.93 (51.65)	0.87	0.05
		MICT	70.52 (68.04)	77.63 (49.88)	0.63	0.11
		UC	109.05 (112.75)	114.4 (98.08)	0.84	0.05
	CD8 Naïve CD103+ (RTE)	HIIT	1.87 (1.34)	6.46 (10.26)	0.22	0.59
		MICT	1.04 (0.43)	0.95 (0.49)	0.49	0.2
		UC	4.55 (4.96)	2.78 (3.38)	0.41	0.39
	CM	HIIT	37.31 (20.55)	44.46 (24.35)	0.6	0.3
		MICT	32.69 (20.5)	41.93 (16.85)	0.19	0.47
		UC	38.94 (21.15)	37.56 (30.14)	0.91	0.04
	EM	HIIT	93.01 (49.08)	74.95 (31.71)	0.1	0.26
		MICT*	65.78 (40.84)	82.29 (45.1)	0.03	0.38
		UC	98.29 (92.73)	87.16 (76.22)	0.57	0.31
	EMRA	HIIT	44.84 (40.85)	41.53 (45.96)	0.63	0.07
		MICT	24.28 (18.12)	23.29 (12.44)	0.67	0.06
		UC	49.74 (42.38)	55.74 (71.31)	0.82	0.1

ISSN: 1742-4933