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Table 4 Relative β2-AR expression (MFI: median fluorescent intensity) in peripheral blood CD4+ and CD8+ T-cell subsets before and after the 12-week intervention. MICT and HIIT did not cause any changes in the expression (MFI; median fluorescence intensity) on lymphocyte subsets and differentiated T cell subsets. [CM=central memory, EM=effector memory, EMRA=Effector Memory CD45RA+] Data are mean (SD). No significant changes were found in response to the intervention (p>0.05)

From: Salutary effects of moderate but not high intensity aerobic exercise training on the frequency of peripheral T-cells associated with immunosenescence in older women at high risk of breast cancer: a randomized controlled trial

Lymphocyte Subset

  

Pre (β2-AR MFI)

Post (β2-AR MFI)

p

|Hedge’s g|

CD4 β2-AR+ T cells

 

HIIT

20.77 (5.22)

23.46 (4.87)

0.23

0.5

  

MICT

22.31 (7.44)

24.05 (4.98)

0.51

0.26

  

UC

18.5 (6.92)

20.27 (6.07)

0.5

0.25

β2-AR+ CD4

β2-AR+ Naïve

HIIT

30.11 (9.90)

38.38 (15.33)

0.25

0.61

  

MICT

33.54 (12.99)

33.36 (6.73)

0.97

0.02

  

UC

29.19 (18.33)

28.99 (11.41)

0.97

0.01

 

β2-AR+ CM

HIIT

22.09 (5.24)

25.49 (6.56)

0.12

0.54

  

MICT

25.44 (7.95)

26.47 (4.95)

0.76

0.15

  

UC

19.31 (6.33)

21.53 (5.27)

0.42

0.36

 

β2-AR+ EM

HIIT

13.05 (2.99)

13.79 (2.29)

0.41

0.26

  

MICT

13.07 (3.25)

15.09 (3.73)

0.14

0.54

  

UC

12.92 (3.67)

13.09 (3.22)

0.9

0.04

 

β2-AR+ EMRA

HIIT

17.78 (8.96)

26.48 (14.83)

0.24

0.67

  

MICT

15.03 (5.12)

25.74 (10.15)

0.07

1.26

  

UC

17.02 (9.21)

19.54 (14.54)

0.65

0.19

CD8 β2-AR+ T cells

 

HIIT

28.73 (11.19)

38.58 (21.61)

0.19

0.54

  

MICT

36.15 (14.17)

39.18 (18.32)

0.66

0.17

  

UC

23.87 (13.47)

128.81 (10.94)

0.38

0.38

β2-AR+ CD8 T cells

β2-AR+ Naïve

HIIT

28.98 (11.94)

41.57 (27.75)

0.23

0.56

  

MICT

34.91 (18.50)

35.28 (22.56)

0.96

0.02

  

UC

27.4 (20.74)

30.11 (16.36)

0.69

0.14

 

β2-AR+ CM

HIIT

52.62 (18.98)

67.57 (27.14)

0.13

0.6

  

MICT

74.54 (33.51)

86.42 (45.42)

0.57

0.28

  

UC

43.86 (21.31)

49.47 (22.42)

0.5

0.5

 

β2-AR+ EM

HIIT

13.96 (4.2)

17.80 (6.54)

0.2

0.66

  

MICT

18.11 (7.14)

16.92 (4.78)

0.74

0.19

  

UC

14.07 (2.65)

15.76 (4.75)

0.42

0.41

 

β2-AR+ EMRA

HIIT

22.71 (13.02)

15.88 (6.1)

0.21

0.63

  

MICT

18.20 (11.77)

21.75 (12.91)

0.07

0.27

  

UC

16.72 (7.13)

12.85 (5.59)

0.27

0.56

γδ T cells (Vδ2+) β2-AR+

 

HIIT

13.63 (12.05)

17.58 (11.38)

0.42

0.32

  

MICT

4.67 (8.83)

11.73 (6.4)

0.11

0.87

  

UC

8.95 (8.51)

10.45 (6.71)

0.7

0.7

NK Cells β2-AR+

 

HIIT

36.29 (11.54)

34.89 (7.69)

0.78

0.13

  

MICT

33.38 (9.22)

21.51 (6.37)

0.51

0.22

  

UC

30.30 (9.23)

30.08 (7.61)

0.91

0.02