Fig. 4
Expression of differentiation, senescence and exhaustion molecules by effector memory RA+ (TEMRA) TCD4 and TCD8 lymphocytes from the Young, Healthy, Smokers and COPD groups by flow cytometry. (A) Expression of CD27 and CD28 on TCD4 and TCD8 lymphocytes. (B) Expression of KLRG1, CD57 and PD1 on TCD4 and TCD8 (C) lymphocytes. Statistical analysis was performed using Kruskal-Wallis and Dunn’s post-test. Boxes and whiskers are shown. * P < 0.05, **, P < 0.01, *** P < 0.001. // indicates change to right axis