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Table 1 List of the phenotype subsets that were analyzed and the terms used to identify each one

From: Age-associated phenotypic imbalance in TCD4 and TCD8 cell subsets: comparison between healthy aged, smokers, COPD patients and young adults

Phenotype

Subset cell denomination*

CD27 + CD28+

Undifferentiated cell

CD27 + CD28-/CD27-CD28+

Partially differentiated cell

CD27-CD28-

Highly differentiated cell

KLRG1-CD57-PD1-

Non-exhausted/non-senescent cell

KLRG1 + CD57-PD1-

Senescent cell

KLRG1 + CD57-PD1+

Exhausted cell

KLRG1-CD57-PD1+

Repeatedly activated cell

KLRG1 + CD57 + PD1+

Non-proliferative exhausted cell

  1. *Terminology according to refs. [26, 41,42,43]