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Table 1 A cohort of hospitalized patients with laboratory-confirmed COVID-19

From: Association between inflammatory cytokines and anti-SARS-CoV-2 antibodies in hospitalized patients with COVID-19

Characteristics

Total

(N = 272)

Patients aged < 65 y

(N = 132)

Patients aged ≥ 65 y

(N = 140)

P-value*

Moderate

(N = 95)

Severe

(N = 37)

Moderate

(N = 78)

Severe

(N = 62)

Male gender

139 (51.1%)

36 (37.9%)

25 (67.6%)

39 (50%)

39 (63%)

0.003

Age (years)

65 (56–72)

54 (43–60)

57 (50–62)

70 (68–75)

72 (69–78)

<  0.01

Baseline symptoms

 Fever

232 (85.3%)

83 (87.4%)

29 (78.4%)

67 (85.9%)

53 (85.5%)

0.62

 Cough

169 (62.1%)

57 (60.0%)

24 (64.9%)

49 (62.8%)

39 (62.9%)

0.95

 Fatigue

103 (37.9%)

33 (34.7%)

16 (43.2%)

25 (32.1%)

29 (46.8%)

0.25

 Shortness of breath

91 (33.5%)

27 (28.4%)

16 (43.2%)

21 (26.9%)

27 (43.5%)

0.07

 Chills

72 (26.5%)

24 (25.3%)

10 (27.0%)

18 (23.1%)

20 (32.3%)

0.67

 Diarrhea

71 (26.1%)

25 (26.3%)

9 (24.3%)

19 (24.4%)

18 (29.0%)

0.93

 Myalgia

63 (23.2%)

24 (25.3%)

10 (27.0%)

15 (19.2%)

14 (22.6%)

0.74

 Headache

35 (12.9%)

15 (15.8%)

5 (13.5%)

6 (7.7%)

9 (14.5%)

0.43

 Nausea

30 (11.0%)

12 (12.6%)

5 (13.5%)

6 (7.7%)

7 (11.3%)

0.71

 Vomit

18 (6.6%)

6 (6.3%)

2 (5.4%)

4 (5.1%)

6 (9.7%)

0.72

 Abdominal pain

11 (4.0%)

5 (5.3%)

1 (2.7%)

3 (3.8%)

2 (3.2%)

0.88

 Blood cough

5 (1.8%)

1 (1.1%)

0 (0.0%)

1 (1.3%)

3 (4.8%)

0.36

Baseline comorbidity

 Hypertension

114 (41.9%)

21 (22.1%)

16 (43.2%)

42 (53.8%)

35 (56.5%)

<  0.01

 Diabetes mellitus

71 (26.1%)

18 (18.9%)

9 (24.3%)

20 (25.6%)

24 (38.7%)

0.05

 Cardiovascular disease

22 (8.1%)

2 (2.1%)

1 (2.7%)

10 (12.8%)

9 (14.5%)

0.008

 Cancer

13 (4.8%)

4 (4.2%)

0 (0.0%)

6 (7.7%)

3 (4.8%)

0.34

 Cerebrovascular disease

10 (3.7%)

1 (1.1%)

1 (2.7%)

3 (3.8%)

5 (8.1%)

0.15

 Chronic bronchitis

8 (2.9%)

2 (2.1%)

0 (0.0%)

3 (3.8%)

3 (4.8%)

0.50

 Cholecystitis

3 (1.1%)

0 (0.0%)

0 (0.0%)

2 (2.6%)

1 (1.6%)

0.44

 COPD#

2 (0.7%)

1 (1.1%)

0 (0.0%)

0 (0.0%)

1 (1.6%)

0.65

Comorbidity count

     

<  0.01

 0

108 (40%)

62 (65%)

15 (40%)

18 (23%)

13 (21%)

 

 1

95 (35%)

18 (19%)

17 (46%)

35 (45%)

25 (40%)

 

 2

46 (17%)

12 (13%)

4 (11%)

17 (22%)

13 (21%)

 

 ≥3

23 (8%)

3 (3%)

1 (3%)

8 (10%)

11 (18%)

 

Clinical outcome

 Death

42 (15.4%)

2 (2.2%)

11 (29.7%)

1 (1.3%)

28 (45.2%)

<  0.01

 Length of hospital stay (days)

21 (12–29)

17 (10–23)

19 (13–31)

23 (18–33)

25 (10–33)

<  0.01

  1. *: P-values were measured by multigroup tests of variables in four patient groups (discrete variables: chi-squared tests, continuous variables: Kruskal-Wallis tests)
  2. #: COPD: chronic obstructive pulmonary disease