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Fig. 4 | Immunity & Ageing

Fig. 4

From: Systemic Listeria monocytogenes infection in aged mice induces long-term neuroinflammation: the role of miR-155

Fig. 4

Differential expression of miR-155-targeted transcription factors in CD11b+ brain cells from young and aged mice. 2 mo C57BL/6 J and 24 mo C57BL/6JN mice were infected i.p. with Lm EGD 2.0 × 105 CFU (n = 9) and 0.3–0.6 × 105 CFU (n = 12), respectively, then received antibiotics beginning 2d p.i. CD11b+ brain cells were obtained from uninfected mice and infected mice 29d p.i. by magnetic sorting. Gene expression was measured by qPCR normalized to snoRNA-135 (A) or by nCounts (B). Statistical analysis was by simple t-test, a p < 0.05 was considered statistically significant

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