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Fig. 4 | Immunity & Ageing

Fig. 4

From: Altered transcriptional responses in the lungs of aged mice after influenza infection

Fig. 4

Age independent, immediate post-infection response module. The ‘brown2’ (n = 67 genes) module is shown. The heatmap and barplots (A) show the average eigengene expression for each sample, which are ordered as increasing timepoints from left to right. Genes were upregulated at day 1 post-infection in both adult and aged mice then returned to pre-treatment levels. Heatmap in (A) and interaction plots in (B) show consistent response in both mouse age classes and the response is restricted to the Day 1 timepoint post infection. The top 30 genes by module membership are shown

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