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Table 2 Summarizing the associations of the candidate and existing ARIP measures with chronological age, biological age, and multimorbidity

From: Evaluation of T-cell aging-related immune phenotypes in the context of biological aging and multimorbidity in the Health and Retirement Study

 

Chronological Age

Biological Age

Multimorbidity

Mortality

Existing ARIP measure

 CD4/CD8

No

No

No (inverse association with increasing levels of multimorbidity)

No

 CD8 + TN

Yes (inverse)

No

No (inverse association with increasing levels of multimorbidity)

No

 CD4 + TN

Yes

Yes

Yes (inverse association with increasing levels of multimorbidity)

Yes

 CD4 + TCM

No

Yes

Yes (positive association with increasing levels of multimorbidity)

No

Candidate ARIP measure

 CD8 + TN/TM

Yes

No

No (inverse association with increasing levels of multimorbidity)

No

 CD4 TN/TM

No

Yes

Yes (inverse association with increasing levels of multimorbidity)

Yes