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Fig. 2 | Immunity & Ageing

Fig. 2

From: Short-term zinc supplementation of zinc-deficient seniors counteracts CREMα - mediated IL-2 suppression

Fig. 2

Baseline zinc status of the cohorts. A-C depicts the population of all seniors compared to the young control in terms of dietary intake (A), serum zinc concentration (B), and labile zinc inside peripheral blood mononuclear cells (PBMC) (C) After applying predefined cut-off values, the cohort of all geriatric inpatients was further subdivided into either zinc-adequate (ZA) elderly or zinc-deficient (ZD) elderly depending on the zinc status measurement method (D-F). Analysis of adjusted zinc diet score and serum zinc of young controls included data of n = 23, intracellular labile zinc includes data obtained from n = 21 young controls. Regarding the elderly, data from n = 31 (A, B), n = 30 (C) and depending on whether ZA elderly or ZD elderly are considered, n = 10, n = 20 (D + F) and n = 9, n = 21 (E), respectively, were included in the analysis. All data are considered unpaired parameters and presented as the mean + SD. Statistical significance was calculated by Mann–Whitney test in the case of non-normal distribution (A), and unpaired t-test in normal distribution (B, C) (all *(p < 0.05)). In D-F ordinary one-way ANOVA followed by Tukey´s post-test was used for calculation with means not sharing any letter (a-c) indicating statistical significance (p < 0.05)

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