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Table 1 Characteristics of the study participants

From: Short-term zinc supplementation of zinc-deficient seniors counteracts CREMα - mediated IL-2 suppression

Characteristics

Young control

N = 23

ZA elderly

N = 10

ZD elderly

N = 21

ZD elderly + ZS

N = 10

Gender1, n (%)

 male

12 (52)

5 (50)

8 (38)

4 (40)

 female

11 (48)

5 (50)

13 (62)

6 (60)

Age2, years

 mean ± SD

24.2 ± 3.0b

84.6 ± 8.1a

85.7 ± 7.0a

86.2 ± 5.0a

 median

23

86.5

85

86.5

 min, max

20, 31

72, 96

71, 100

80, 94

BMI3, kg/m2

 mean ± SD

23.5 ± 2.1a

24.6 ± 4.4a

25.9 ± 5.8a

24.2 ± 5.4a

 median

24

24.8

24.7

24.5

 min, max

18.4, 26.3

16.2, 33.8

14.9, 41.1

14.9, 35.2

Diet form, n (%)

 omnivorous

16 (70)

10 (100)

21 (100)

10 (100)

 vegetarian

6 (26)

0 (0)

0 (0)

0 (0)

 vegan

1 (4)

0 (0)

0 (0)

0 (0)

Major hospital admission cause4, n (%)

 geriatric trauma

-

5 (50)

12 (57)

5 (50)

 cardiovascular disease

-

2 (20)

8 (38)

5 (50)

 others (metabolic, respiratory, or neurological disease)

-

3 (30)

1 (5)

0 (0)

Length of hospital stay3, days

 mean ± SD

-

13.3 ± 6.8a

25.8 ± 18.7a

23 ± 10.7a

 median

-

13.5

20

19.5

 min, max

-

5, 26

4, 99

4, 44

Major pre-existing conditions5, n (%)

 cardiovascular disease

-

10 (100)

21 (100)

10 (100)

 metabolic disease

-

9 (90)

13 (62)

8 (80)

 kidney disease

-

3 (30)

12 (57)

5 (50)

 musculoskeletal disease

-

5 (50)

9 (43)

5 (50)

 respiratory disease

-

2 (20)

8 (38)

3 (30)

 others (neurological, digestive, urogenital disease)

-

8 (80)

17 (81)

7 (70)

Hospital Frailty Risk score3

 mean ± SD

-

9.0 ± 6.4a

8.8 ± 6.0a

7.5 ± 3.8a

 median

-

7.7

8.5

7.2

 min, max

-

1.4, 21

0, 25.1

2.9, 14.8

Medication used at hospital admission5, n (%)

 proton pump inhibitors

-

7 (70)

18 (86)

8 (80)

 diuretics

-

6 (60)

17 (81)

7 (70)

 anticoagulants/PAI

-

6 (60)

15 (71)

8 (80)

 analgesics

-

4 (40)

15 (71)

7 (70)

 ACEi/ARB

-

7 (70)

12 (57)

4 (40)

 beta-blockers

-

7 (70)

10 (48)

4 (40)

 other antihypertensives

-

1 (10)

9 (43)

2 (20)

 statins

-

2 (20)

9 (43)

6 (60)

 antidiabetics

-

2 (20)

3 (14)

3 (30)

 steroids

-

1 (10)

2 (10)

2 (20)

 others

-

5 (50)

14 (67)

6 (60)

  1. Abbreviations: BMI Body mass index, ZA Zinc-adequate, ZD Zinc-deficient, ZS Zinc supplementation, PAI Platelet aggregation inhibitors, ACEi Angiotensin-converting enzyme inhibitors, ARB Angiotensin-II receptor blockers 
  2. 1 Chi-square test (in this case: all p > 0.05, see text for details)
  3. 2 Kruskal–Wallis test and Dunn´s post-test. Means not sharing any letter (a or b) indicate statistical significance (p < 0.05)
  4. 3 One-way ANOVA and Tukey´s post-test. Means not sharing any letter (a or b) indicate statistical significance (p < 0.05)
  5. 4 under categories; while a hospitalization can, of course, have several reasons, for the sake of clarity we decided to indicate the most predominant one in each case
  6. 5 under categories