Fig. 3
From: Inflammation and cell-to-cell communication, two related aspects in frailty
IL-6 plasma levels significantly increase with frailty. (A) IL-6 plasma levels are significantly higher in all Fr (n = 65) compared to nFr (n = 64) subjects (***p < 0.001). IL-6 plasma levels were analyzed according to gender separation; in (B) IL-6 plasma levels in Fr male (n = 33) significantly increase compared to nFr male (n = 32) subjects (**p < 0.01). In (C) are reported data from Fr female (n = 32) compared to nFr female (n = 32) subjects, a statistically significant increase is observed in Fr vs. nFr subjects (***p < 0.001). Statistical analysis was performed using the Mann–Whitney U test (non-parametric) for comparisons between two groups using GraphPad Prism8 software. A p < 0.05 was considered statistically significant